With an area of 12 sq km, Tianhe Central Business District is located at the crossroads of Guangzhou's new central axis and the Pearl River. It is a major part of Guangzhou's plans to develop into a national central city and is one of the key central business districts within the Guangdong-Hong Kong-Macao Greater Bay Area.

The area features numerous commercial office buildings, including landmarks like the Guangzhou International Financial Center and the Guangzhou Chow Tai Fook Financial Center. Tianhe CBD functions as a comprehensive hub for business, finance, and international affairs, attracting a significant concentration of Fortune Global 500 investments, corporate headquarters, and a wide array of foreign consulates, business associations, and regional bank headquarters.

Investment is welcomed in key sectors such as company headquarters, modern business and trade, business and financial services.